Our society calls for Islamic structures, equal chance, justice, and support for the disadvantaged in creating businesses. These issues can be facilitated within the framework of Islamic banking which in turn doubles the growth of entrepreneurial activities. The current research was carried out with the aim of identifying the factors affecting entrepreneur-oriented Islamic banking with a meta-synthesis approach. To this end, 47 studies were extracted from various scientific databases for the period 1990-2021 and analyzed using the seven-step model of Sandelowski and Barroso, to extrapolate the relevant concepts and categories. Based on the research findings, 18 concepts were identified in the form of 7 categories, which were divided into economic and social factors. The categories of changing risk management in investments, granting credits based on Islamic contracts, changing the pattern of bank deposit reserves, respecting the rights of beneficiaries, managing financial markets based on Islamic contracts, establishing justice-oriented contexts, and paying attention to the culture and knowledge based on Islam are identified as the factors affecting Islamic banking.